Double disk transdermal process
AssigneeMylan Inc.
InventorsGaurav Thakersi TOLIA, Malachi PLACHTA, Grant HENDERSON, Brad L. BARNETT
Life of this patent
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Abstract
A double disk dermal device for administration of one or more active agents to the skin or mucosa of a host, in particular a patch is described including: a) active reservoir film layer; b) a backing overlay adjacent to the active reservoir film layer extending beyond the perimeter of the reservoir layer in all directions; c) second overlay backing layer with a coating of pressure sensitive adhesive which is adjacent to the first backing overlay extending beyond the perimeter of the first backing overlay in all directions; and d) a removable release liner. A method of making the device is also provided.
Claims19
A process for preparing a dermal device comprising the steps of:
- fixing a first layer to a first release liner;
- placing a second material adjacent to the first layer to form an active inner reservoir layer, wherein the second material brings structural integrity to the active inner reservoir layer;
- winding the exposed side of the active inner reservoir layer on a second release liner to form a dual release liner unit;
- kiss-cutting the active inner reservoir layer into suitable size patches;
- and
- laminating a backing layer extending beyond the perimeter of the active inner reservoir layer on the exposed side of the active inner reservoir layer;
- wherein the process is performed using a continuous manufacturing process.
A process for preparing a dermal device comprising the steps of:
- coating a wet adhesive film on a first release liner;
- placing a second material adjacent to the wet adhesive film to form an active inner reservoir layer, wherein the second material brings structural integrity to the active inner reservoir layer;
- drying the active inner reservoir layer on the first release liner;
- winding the exposed side of the active inner reservoir layer on a second release liner to form a dual release liner unit;
- slitting the dual release liner unit into suitable size patches;
- removing the second release liner to expose one side of the active inner reservoir layer;
- kiss-cutting the active inner reservoir layer into suitable size patches and
- laminating a backing layer extending beyond the perimeter of the active inner reservoir layer on the exposed side of the active inner reservoir layer,
- wherein the process is performed using a continuous manufacturing process.
A process for preparing a dermal device comprising the steps of:
- coating a wet adhesive film on a first release liner;
- drying the wet adhesive film on the first release liner to form an active inner reservoir layer;
- kiss-cutting the active inner reservoir layer into suitable size patches and
- placing a backing ring extending beyond the perimeter of the active inner reservoir layer on the exposed side of the active inner reservoir layer,
- laminating the exposed side of the backing ring with an outer disk adhesive layer;
- wherein the process is performed using a continuous manufacturing process.
A process for preparing a dermal device comprising the steps of:
- coating a wet adhesive film on a first release liner;
- drying the wet adhesive film on the first release liner to form an active inner reservoir layer;
- laminating the active inner reservoir layer with a first backing film layer coated with an adhesive tie layer that brings structural integrity to the waste rewind;
- winding the exposed side of the adhesive tie layer on a second release liner to form a dual release liner unit;
- removing the second release liner to expose one side of the adhesive tie layer;
- kiss-cutting the laminated active inner reservoir layer into suitable size patches;
- laminating a second backing layer extending beyond the perimeter of the active inner reservoir layer on the exposed side of the adhesive tie layer;
- and
- laminating the second backing layer with an outer disk adhesive layer;
- wherein the process is performed using a continuous manufacturing process.
Dependencies are inferred from the claim text.