Method of using time to effect (tte) to estimate the optimum cryodose to apply to a pulmonary vein
AssigneeMedtronic CryoCath LP
InventorJean-Pierre LALONDE
Life of this patent
Estimating the term…
Abstract
A system and method for determining the optimum dose of cryotreatment to an area of target tissue to achieve isolation based on the time to effect (TTE). The system may generally include a treatment device, a sensing device, and a processor programmed to calculate the optimum dose of cryotreatment, in seconds, based on TTE. The TTE may be based on electrical signals received by the processor from the sensing device. The processor may be further programmed to automatically terminate a cryoablation procedure when the optimum dose of cryotreatment has elapsed. The optimum dose of cryotreatment may be the time, in seconds, it takes to achieve isolation, which may be the time it takes for an area of tissue to reach approximately −20° C.
Claims26
A cryoablation system, the system comprising:
- a processor configured to:
- receive mapping signals;
- calculate a time to effect (TTE) based on the received mapping signals;
- and
- determine a recommended cryoablation dose based on the TTE.
A cryoablation system, the system comprising:
- a cryotreatment device including a treatment element;
- a sensing device including a plurality of mapping elements, each of the plurality of mapping elements being configured to obtain mapping signals from an area of tissue;
- and
- a processor in communication with the cryotreatment device and the sensing device, the processor being programmed to:
- receive the mapping signals from the plurality of mapping elements;
- calculate a time to effect (TTE) based on the received mapping signals;
- and
- determine a recommended cryoablation dose based on the TTE.
A cryoablation system, the system comprising:
- a cryotreatment device including an elongate body having a proximal portion, a distal portion, a central lumen, and a treatment element coupled to the distal portion of the cryotreatment device elongate body;
- a sensing device including an elongate body having a proximal portion and a distal portion and a plurality of mapping elements coupled to the distal portion of the mapping device elongate body, each of the plurality of mapping elements being configured to obtain mapping signals from an area of tissue, the elongate body of the sensing device being longitudinally movable within the central lumen of the cryotreatment device;
- and
- a processor in communication with the cryotreatment device and the sensing device, the processor being programmed to:
- receive the mapping signals from the plurality of mapping elements;
- calculate a time to effect (TTE) based on the received mapping signals, TTE being achieved when one or more peak amplitudes of the received mapping signals decreases by half or a time between two or more peak amplitudes of the received mapping signals increases by more than 20%;
- correlating the TTE to a time to isolation (TTI), the TTI being the time it takes an area of tissue to reach approximately −20° C. and at least 75% cell death within the area of tissue;
- and
- determine a recommended cryoablation dose based on the TTE.
Dependencies are inferred from the claim text.