# US 2017/0285018 A1 · Sensor, method of forming a sensor and use thereof > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2017/0285018 A1 - Document ID: US20170285018A1 - Status: Published application - Kind: A1 - Application number: 15/475,313 - Filed: 2017-03-31 - Published: 2017-10-05 - Earliest claimed: 2016-03-31 - Assignees: Cambridge Display Technology Limited - Applicants: Cambridge Display Technology, Ltd. - Inventors: RICHARD WILSON; Jonathan Behrendt - Web page: https://patentgrep.com/patent/US20170285018A1 ## CPC - G01N 33/5438: {Electrodes} - B05D 1/005: {Spin coating} - B05D 3/007: {After-treatment} - G01N 27/226: {Construction of measuring vessels; Electrodes therefor} - G01N 27/4145: {specially adapted for biomolecules, e.g. gate electrode with immobilised receptors} - G01N 2333/765: Serum albumin, e.g. HSA - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - B05D: PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL (conveying articles or workpieces through baths of liquid B65G, e.g. B65G49/02) ## Abstract A method of forming a sensor comprising a single layer or multilayer structure; a fluorinated layer having a fluorinated surface on the single layer or multiple layer structure; and a receptor having a fluorinated group on the fluorinated surface, the method comprising treating the fluorinated surface with a surfactant and either depositing the receptor having a fluorinated group onto the fluorinated surface from a formulation comprising one or more solvents in which the receptor is dissolved or dispersed, or depositing a fluorinated compound comprising a fluorinated group onto the fluorinated surface from a formulation comprising one or more solvents in which the fluorinated compound is dissolved or dispersed, and reacting the fluorinated compound or a derivative thereof with a receptor comprising a reactive group to form the receptor having the fluorinated group. ## Claims ### Claim 1 A method of forming a sensor comprising a single layer or multilayer structure; a fluorinated layer having a fluorinated surface on the single layer or multiple layer structure; and a receptor having a fluorinated group on the fluorinated surface, the method comprising treating the fluorinated surface with a surfactant and either: depositing the receptor having a fluorinated group onto the fluorinated surface from a formulation comprising one or more solvents in which the receptor is dissolved or dispersed; or depositing a fluorinated compound comprising a fluorinated group onto the fluorinated surface from a formulation comprising one or more solvents in which the fluorinated compound is dissolved or dispersed, and reacting the fluorinated compound or a derivative thereof with a receptor comprising a reactive group to form the receptor having the fluorinated group. ### Claim 2 (depends on 1) A method according to claim 1 wherein the formulation comprises the surfactant. ### Claim 3 (depends on 1) A method according to claim 1 wherein the fluorinated surface is treated with the surfactant before deposition of the fluorinated compound or fluorinated receptor. ### Claim 4 (depends on 1) A method according to claim 1 wherein the surfactant is an amphiphilic polymer. ### Claim 5 (depends on 1) A method according to claim 1 wherein the surfactant is a surface active protein. ### Claim 6 (depends on 5) A method according to claim 5 wherein the surface active protein is bovine serum albumin. ### Claim 7 (depends on 1) A method according to claim 1 wherein the one or more solvents comprise or consist of water. ### Claim 8 (depends on 1) A method according to claim 1 wherein the fluorinated layer is a layer of fluorinated material deposited on a surface of the single layer or multilayer structure. ### Claim 9 (depends on 8) A method according to claim 8 wherein the fluorinated layer has a thickness in the range of 5 nm-10 microns. ### Claim 10 (depends on 8) A method according to claim 8 wherein the fluorinated layer comprises a fluorinated polymer. ### Claim 11 (depends on 8) A method according to claim 8 wherein the fluorinated polymer is crosslinked. ### Claim 12 (depends on 1) A method according to claim 1 wherein the fluorinated surface is a fluorinated self-assembled monolayer formed at a surface of the single layer or multilayer structure. ### Claim 13 (depends on 1) A method according to claim 1 wherein the fluorinated group is a perfluoroalkyl group. ### Claim 14 (depends on 1) A method according to claim 1 wherein the receptor is selected from DNA, PNA, RNA, peptides, carbohydrates, antibodies, antigens, enzymes and proteins. ### Claim 15 A sensor comprising: a structure configured to detect a change in an electrical property in a layer thereof; a fluorinated layer on a surface of the structure; and a receptor bound to a fluorinated group on an outer surface of the fluorinated layer. ### Claim 16 (depends on 15) A sensor according to claim 15 wherein the detector is a thin film transistor comprising a gate electrode; source and drain electrodes; a dielectric layer between the gate electrode and the source and drain electrodes; and a semiconductor layer extending between the source and drain electrodes. ### Claim 17 (depends on 16) A sensor according to claim 16 wherein the thin film transistor is a bottom gate thin film transistor. ### Claim 18 (depends on 16) A sensor according to claim 16 wherein the thin film transistor is an organic thin film transistor. ### Claim 19 (depends on 16) A sensor according to claim 16 wherein the fluorinated layer is adjacent to and in contact with the semiconductor layer. ### Claim 20 A sensor comprising: a structure configured to detect a change in an optical property in a layer thereof; a fluorinated layer on a surface of the structure; and a receptor bound to a fluorinated group on an outer surface of the fluorinated layer.