# US 2017/0281018 A1 · Determining arterial wall property with blood flow model > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2017/0281018 A1 - Document ID: US20170281018A1 - Status: Published application - Kind: A1 - Application number: 15/479,465 - Filed: 2017-04-05 - Published: 2017-10-05 - Earliest claimed: 2016-04-05 - Assignees: Siemens Healthcare GmbH - Inventors: Martin Kramer; Lucian Mihai Itu; Viorel Mihalef; Puneet Sharma - Web page: https://patentgrep.com/patent/US20170281018A1 ## CPC - A61B 5/02007: {Evaluating blood vessel condition, e.g. elasticity, compliance} - A61B 5/026: Measuring blood flow {(A61B3/1233, A61B3/1241 take precedence)} - A61B 5/7278: {Artificial waveform generation or derivation, e.g. synthesizing signals from measured signals} - G16H 50/50: for simulation or modelling of medical disorders - A61B 5/022: by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers - A61B 6/504: {for diagnosis of blood vessels, e.g. by angiography} - A61B 6/507: {for determination of haemodynamic parameters, e.g. perfusion CT} - A61B 8/06: Measuring blood flow - A61B 8/488: {involving Doppler signals} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA ## Abstract An estimation of arterial wall properties is provided. A method for determining a wall property of an artery such as an aorta includes acquiring patient data and extracting physical data from the patient data. The physical data is applied to a blood flow model of the aorta to obtain an individual blood flow model. The wall property of the artery is directly or indirectly determined from the individual blood flow model. ## Claims ### Claim 1 A method for determining a wall property of an artery, the method comprising: acquiring patient data; and extracting physical data from the patient data; obtaining an individual blood flow model, the obtaining comprising applying the physical data to a blood flow model of the artery; and determining the wall property of the artery directly or indirectly from the individual blood flow model. ### Claim 2 (depends on 1) The method of claim 1, wherein acquiring the patient data includes medical imaging. ### Claim 3 (depends on 1) The method of claim 1, wherein acquiring the patient data includes a non-invasive measurement. ### Claim 4 (depends on 1) The method of claim 1, wherein the physical data includes an anatomical model of the artery, blood flow data, or the anatomical model of the artery and the blood flow data. ### Claim 5 (depends on 1) The method of claim 1, wherein the blood flow model is a fluid-structure interaction blood flow model. ### Claim 6 (depends on 1) The method of claim 1, wherein the blood flow model is based on a mass conservation equation and a longitudinal momentum conservation equation, the mass conservation equation and the longitudinal momentum conservation equation both relying on a time-varying cross-sectional area and a time-varying flow-rate, and wherein the mass conservation equation and the longitudinal momentum conservation equation are coupled by a state equation. ### Claim 7 (depends on 1) The method of claim 1, further comprising visualizing the wall property on an image of the artery, wherein the wall property is varying spatially with geometric coordinates. ### Claim 8 (depends on 1) The method of claim 1, wherein determining the wall property of the artery comprises directly determining a local area compliance as the wall property from the blood flow model. ### Claim 9 (depends on 1) The method of claim 1, further comprising determining a local wave speed of blood in the artery from the blood flow model, wherein determining the wall property of the artery comprises estimating the wall property from the local wave speed. ### Claim 10 (depends on 1) The method of claim 1, wherein the artery is an aorta. ### Claim 11 A device for determining a wall property of an artery, the device comprising: an acquisition device configured to acquire patient data; and a processor configured to: extract physical data from the patient data; obtain an individual blood flow model, the obtainment of the individual blood flow model comprising application of the physical data to a blood flow model of the artery; and determine the wall property of the artery directly or indirectly from the individual blood flow model. ### Claim 12 (depends on 11) The device of claim 11, wherein the artery is an aorta. ### Claim 13 (depends on 11) The device of claim 11, wherein the acquisition device is a medical imaging device, and wherein acquisition of the patient data includes medical imaging. ### Claim 14 (depends on 11) The device of claim 11, wherein the acquisition of the patient data includes a non-invasive measurement. ### Claim 15 (depends on 11) The device of claim 11, wherein the physical data includes an anatomical model of the artery, blood flow data, or the anatomical model of the artery and the blood flow data. ### Claim 16 (depends on 11) The device of claim 11, wherein the blood flow model is a fluid-structure interaction blood flow model. ### Claim 17 (depends on 11) The device of claim 11, wherein the blood flow model is based on a mass conservation equation and a longitudinal momentum conservation equation, the mass conservation equation and the longitudinal momentum conservation equation both relying on a time-varying cross-sectional area and a time-varying flow-rate, and wherein the mass conservation equation and the longitudinal momentum conservation equation are coupled by a state equation.