# US 2017/0281007 A1 · Disease diagnosis and skin age measurement apparatus using laser irradiation device and detachable handpiece used in the same

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- Number: US 2017/0281007 A1
- Document ID: US20170281007A1
- Status: Published application
- Kind: A1
- Application number: 15/258,253
- Filed: 2016-09-07
- Published: 2017-10-05
- Earliest claimed: 2016-04-04
- Assignees: Speclipse, Inc.
- Applicants: Speclipse, Inc.
- Inventors: Sung Hyun PYUN; Wanki MIN
- Web page: https://patentgrep.com/patent/US20170281007A1

## CPC

- A61B 5/0077: {Devices for viewing the surface of the body, e.g. camera, magnifying lens}
- A61B 5/0075: {by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy (A61B5/0071 takes precedence)}
- A61B 5/441: {Skin evaluation, e.g. for skin disorder diagnosis}
- G01J 3/0208: {using focussing or collimating elements, e.g. lenses or mirrors; performing aberration correction}
- G01J 3/021: {using plane or convex mirrors, parallel phase plates, or particular reflectors}
- G01J 3/0218: {using optical fibers}
- G01J 3/024: {using means for illuminating a slit efficiently (e.g. entrance slit of a spectrometer or entrance face of fiber)}
- G01J 3/0248: {using a sighting port, e.g. camera or human eye}
- G01J 3/0291: {Housings; Spectrometer accessories; Spatial arrangement of elements, e.g. folded path arrangements}
- G01J 3/2803: {using photoelectric array detector}
- G01J 3/2823: {Imaging spectrometer}
- G01J 3/443: Emission spectrometry
- A61B 5/7246: {using correlation, e.g. template matching or determination of similarity}
- A61B 5/7282: {Event detection, e.g. detecting unique waveforms indicative of a medical condition (cough events A61B5/0823; seizures A61B5/4094; sleep apnoea A61B5/4818)}
- G01J 2003/282: {Modified CCD or like}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01J: MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY (light sources F21, H01J, H01K, H05B; investigating properties of materials by optical means G01N)

## Abstract

A disease diagnosis and skin age measurement apparatus includes: a first light collection unit; a second light collection unit; a spectrometer configured to measure a spectrum of the light which is collected by the second light collection unit; a spectrum data comparison unit for disease diagnosis configured to compare the spectrum measured by the spectrometer and reference spectrum data for disease diagnosis; a CCD; an image data comparison unit configured to compare the digital image converted by the CCD and a reference image; a disease diagnosis unit configured to determine whether there is a disease in the body tissue; and/or a spectrum data comparison unit for skin age measurement configured to measure skin age by comparing a spectrum measured by the spectrometer and reference spectrum data for skin age measurement, wherein the light projected onto the body tissue is collimate light.

## Claims

### Claim at position 1

-19. (canceled)

### Claim 20

A disease diagnosis apparatus for collecting light which is generated when light is projected onto body tissue and diagnosing a disease, the apparatus comprising:
a first light collection unit configured to collect a part of the generated light;
a second light collection unit configured to collect a part of the generated light;
a spectrometer configured to analyze a spectrum of the light which is collected by the second light collection unit;
a spectrum data comparison unit configured to compare the spectrum analyzed by the spectrometer and reference spectrum data;
a CCD configured to convert the light collected by the first light collection unit into a digital image;
an image data comparison unit configured to compare the digital image converted by the CCD and a reference image; and
a disease diagnosis unit configured to determine whether there is a disease in the body tissue based on at least one of a comparison result of the spectrum data comparison unit and a comparison result of the image data comparison unit,
wherein the light projected onto the body tissue is a collimated light.

### Claim 21 (depends on 20)

The apparatus of claim 20, further comprising a related data generation unit configured to generate related data which defines a relationship between the digital image converted by the CCD and the spectrum data analyzed by the spectrometer.

### Claim 22 (depends on 20)

The apparatus of claim 20, further comprising an SELIES (Surface Enhanced Laser Induced Emission Spectroscopy) film,
wherein the SELIES (Surface Enhanced Laser Induced Emission Spectroscopy) film has a function of enhancing a signal intensity of the generated light, and
wherein the SELIES (Surface Enhanced Laser Induced Emission Spectroscopy) film is disposed on the body tissue.

### Claim 23 (depends on 22)

The apparatus of claim 22, wherein the SELIES (Surface Enhanced Laser Induced Emission Spectroscopy) film comprises a substrate and a layer for enhancing the signal intensity of the generated light,
wherein the layer is temporarily or fixedly formed on the surface of the substrate.

### Claim 24 (depends on 20)

The apparatus of claim 20, wherein the second light collection unit comprises an optical module configured to provide a part of the generated light collected by the second light collection unit to an optical fiber connected to the spectrometer.

### Claim 25 (depends on 20)

The apparatus of claim 20, wherein the first light collection unit comprises an optical module configured to provide a part of the generated light collected by the first light collection unit to the CCD.

### Claim 26

A disease diagnosis apparatus for collecting light which is generated when light is projected onto body tissue and diagnosing a disease, the apparatus comprising:
a complex light collection unit configured to collect at least part of the generated light;
a spectrometer configured to analyze a spectrum of a part of the light which is collected by the complex light collection unit;
a spectrum data comparison unit configured compare the spectrum analyzed by the spectrometer and reference spectrum data;
a CCD configured to convert a part of the light collected by the complex light collection unit into a digital image;
an image data comparison unit configured to compare the digital image converted by the CCD and a reference image; and
a disease diagnosis unit configured to determine whether there is a disease in the body tissue based on at least one of a comparison result of the spectrum data comparison unit and a comparison result of the image data comparison unit, and
wherein the light projected onto the body tissue is a collimated beam.

### Claim 27 (depends on 26)

The apparatus of claim 26, further comprising a related data generation unit configured to generate related data which defines a relationship between the digital image converted by the CCD and the spectrum data analyzed by the spectrometer.

### Claim 28 (depends on 26)

The apparatus of claim 26, further comprising an SELIES (Surface Enhanced Laser Induced Emission Spectroscopy) film,
wherein the SELIES (Surface Enhanced Laser Induced Emission Spectroscopy) film has a function of enhancing a signal intensity of the generated light, and
wherein the SELIES (Surface Enhanced Laser Induced Emission Spectroscopy) film is disposed on the body tissue.

### Claim 29 (depends on 28)

The apparatus of claim 28, wherein the SELIES (Surface Enhanced Laser Induced Emission Spectroscopy) film comprises a substrate and a layer for enhancing the signal intensity of the generated light,
wherein the layer is temporarily or fixedly formed on the surface of the substrate.

### Claim 30 (depends on 26)

The apparatus of claim 26, wherein the complex light collection unit is configured to split the collected light into the spectrometer and the CCD.

### Claim 31 (depends on 30)

The apparatus of claim 30, wherein the complex light collection unit comprises a first optical module configured to split a part of the collected light into a first direction and a second direction, and transmit the light, a second optical module configured to receive at least part of the light transmitted from the first optical module in the first direction; and a third optical module configured to receive at least part of the light transmitted from the first optical module in the second direction,
wherein the second optical module is configured to provide the at least part of the light received from the first optical module to an optical fiber connected with spectrometer, and
wherein the third optical module is configured to provide the at least part of the light provided from the first optical module to the CCD.

### Claim 32 (depends on 31)

The apparatus of claim 31, wherein the third optical module comprises two optical devices,
wherein a first optical device of the two optical devices is configured to receive at least part of the light which is generated when the light is projected onto the body tissue, and provide the light to a second optical device of the two optical devices,
wherein the second optical device is configured to split the light received from the first optical device into the first direction and the second direction,
wherein the second optical module is configured to receive at least part of the light split into the first direction, and the third optical module is configured to receive at least part of the light split in the second direction.

### Claim 33 (depends on 31)

The apparatus of claim 31, wherein the first optical module comprises two optical devices,
wherein a first optical device of the two optical devices is configured to receive at least part of the light which is generated when the light is projected onto the body tissue, and split the light into the first direction and the second direction,
wherein a second optical device of the two optical devices is configured to provide at least part of the light split into the first direction to the second optical module, and the third optical module is configured to receive at least part of the light split into the second direction.

### Claim 34

A detachable handpiece for disease diagnosis, which is attachable to or detachable from a laser irradiation device which is able to perform an operation for medical or beauty care using light, the detachable handpiece comprising:
a body part having a cylindrical shape, the body part comprising:
a path formed therein to allow light to travel,
a generated light entering part configured to receive light which is generated when light is projected onto body tissue by the laser irradiation device, and
a connection part detachably connected with the laser irradiation device;
a CCD disposed in the body part to generate a digital image; and
a light collection unit configured to split the generated light entering through the generated light entering part into a spectrometer and the CCD,
wherein the CCD is configured to generate the digital image corresponding to the light provided from the light collection unit, and
wherein the laser projected onto the body tissue by the laser irradiation device is a collimated beam,
wherein the light collection unit comprises:
an optical module configured to split at least part of the generated light entering through the generated light entering part into a first direction and a second direction, and transmit the light;
an optical module configured to provide the light transmitted in the first direction to an optical fiber connected to the spectrometer; and
an optical module configured to provide the light transmitted in the second direction to the CCD.

### Claim 35 (depends on 34)

The detachable handpiece of claim 34, wherein the body part comprises a first part having a space to allow light to travel therein, a second part having a space to allow light to travel therein, and a third part having a space to allow light to travel therein,
wherein at least part of the optical module for providing the light transmitted in the first direction to the optical fiber is disposed in the first part,
wherein the optical module for providing the light transmitted in the second direction to the CCD is disposed in the second part,
wherein the optical module for splitting at least part of the generated light entering through the generated light entering part into the first direction and the second direction and transmitting the light is disposed in the third part,
wherein the light projected onto the body tissue enters through one end of the third part, travels through the inner space formed in the third part, and then is projected through the generated light entering part formed at the other end of the third part.

### Claim 36 (depends on 35)

The detachable handpiece of claim 35, wherein the third part is disposed in the center of the body part, and the first part and the second part are disposed to enclose the third part.

### Claim 37 (depends on 36)

The detachable handpiece of claim 36, wherein the first part and the second part are disposed to face each other.

### Claim 38 (depends on 35)

The detachable handpiece of claim 35, wherein the optical module for providing the light transmitted in the first direction to the optical fiber comprises:
one or more optical devices configured to change a direction of light, and
an optical device configured to place a focal point of light the direction of which has been changed by the one or more optical devices on the optical fiber.

### Claim 39 (depends on 34)

The detachable handpiece of claim 34, wherein the generated light entering through the generated light entering part is a collimated beam.
