Transdifferentiated tissue graft
OwnerClaudia Eder, Michael Ogoninventors
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Abstract
The invention provides a method of producing a connective tissue graft suitable for correcting a connective tissue defect, comprising determining the size and shape of a tissue defect, obtaining a fat tissue from a patient modelled to fit the size and shape of the tissue defect, contacting the fat tissue with one or more connective tissue specific growth or differentiation factors; and kits for such a method.
Claims17
1-17. (canceled)
A method of producing a bioengineered connective tissue graft by direct transdifferentiation of a donor connective tissue, preferably fat tissue, into another connective tissue type comprising contacting the donor connective tissue in vitro or in vivo by one or more administered connective tissue specific growth or differentiation factor.
A method of producing a connective tissue graft suitable for correcting a connective tissue defect, comprising deter-mining the size and shape of a tissue defect, treating a donor connective tissue, preferably fat tissue, obtained from a patient by, in any order:
- modelling donor connective tissue, preferably fat tissue, to fit the size and shape of the tissue defect and contacting the donor connective tissue, preferably fat tissue, with one or more connective tissue specific growth or differentiation factors, thereby initiating differentiation of the tissue graft into another connective tissue.
Dependencies are inferred from the claim text.