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US 2017/0248600 A1Published application
Method to identify antigen-specific immune cells
AssigneeRareCyte, Inc.
InventorLance U'Ren
Life of this patent
Estimating the term…
Abstract
This disclosure is directed to methods for retrieving and using at least one lymphocyte. Additionally, cell receptor sequences identified with this strategy could be used for antibody development, TCR discovery, or appropriate therapeutics development or evaluation.
Claims20
A method comprising:
- collecting a sample suspected of containing at least one immune cell;
- re-stimulating the at least one immune cell with an aliquot of an antigen, the at least one immune cell having been stimulated with the antigen prior to at least the re-stimulating step;
- retrieving the at least one immune cell that was re-stimulated during the re-stimulating step,
- wherein the at least one immune cell is a B cell or a T cell.
1 more element
A method comprising:
- collecting a sample suspected of containing at least one immune cell;
- re-stimulating the at least one immune cell with an aliquot of an antigen, the at least one immune cell having been stimulated with the antigen prior to at least the re-stimulating step;
- obtaining an image of the at least one immune cell that was re-stimulated during the re-stimulating step,
- wherein the at least one immune cell is a B cell or a T cell.
1 more element
Dependencies are inferred from the claim text.