Marker For Depression, Assay Method, Method For Determining Depression, Screening Method For Antidepressants, And Kit
AssigneeMeijo University
InventorsToshitaka NABESHIMA, Akihiro Mouri, Yukihiro Noda
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Abstract
Disclosed herein are a method and a kit using a novel marker associated with depression. The marker for depression includes one or more selected from a noradrenaline transporter and a dopamine transporter. The method for determining depression includes a step of examining an expression level of the marker for depression in a blood sample collected from a subject.
Claims12
(canceled)
A method for determining depression, comprising a step of examining an expression level of a marker for depression in a blood sample collected from a subject, wherein the marker for depression comprises one or more selected from a noradrenaline transporter or a dopamine transporter.
A method for determining depression, comprising a step of analyzing the following (1) and (2) in a blood sample collected from a subject:
- (1) a noradrenaline transporter expression level;
- and
- (2) a ratio of a ubiquitinated and/or phosphorylated noradrenaline transporter.
A kit comprising a detector of a marker for depression, wherein the marker for depression comprises one or more selected from a noradrenaline transporter or a dopamine transporter.
An assay method for assisting diagnosis of depression, comprising a step of examining an expression level of a marker for depression, wherein the marker for depression comprises one or more selected from a noradrenaline transporter or a dopamine transporter.
An assay method for assisting diagnosis of depression, comprising a step of examining ubiquitination and/or phosphorylation of a marker for depression, wherein the marker for depression comprises one or more selected from a noradrenaline transporter or a dopamine transporter.
A screening method for antidepressants, comprising a step of examining a change in an expression level of a marker for depression, wherein the marker for depression comprises one or more selected from a noradrenaline transporter or a dopamine transporter.
Dependencies are inferred from the claim text.