Mesenchymal Stem Cell Diagnostic Testing
OwnerJeremy B. Vines, Howard P. Walthall, Jr.inventors
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Abstract
Diagnostic tests and methods to assess the characteristics of a patient's native stem cell populations. A reference cell source may be selected for testing, to determine the relative health and potency of the cell population derived from that cell source based on standardized testing protocols, and to use the results to evaluate the systemic stem cell health status of the patient across the many different cell populations residing in different tissues in the body.
Claims22
A method to assess the characteristics of a patient's native stem cell populations, comprising the steps of:
- obtaining a Reference Cell Source from a patient;
- isolating stem cells from the Referenced Cell Source;
- culturing the isolated stem cells in a Cell Propagation Medium;
- measuring the potency of the isolated stem cells using one or more techniques;
- calculating an index value using the outcomes of such potency measurements;
- and
- determining an assessment value for the patient's isolated stem cells based on a comparison of their index value to a range of values determined from other subjects using the same standardized techniques.
A kit for assessing the characteristics of a patient's native stem cell populations comprising:
- at least one blood collection tube;
- at least one stem cell-specific antibody, wherein each antibody conjugated to a label;
- a Cell Propagation Medium;
- at least one Supplement;
- and
- at least one Growth Factor-specific antibody, wherein each antibody conjugated to a label.
Dependencies are inferred from the claim text.