Enhanced processive cellulases
AssigneeAlliance for Sustainable Energy, LLC
InventorsWilliam S. ADNEY, Gregg T. BECKHAM, Eric JARVIS, Michael E. HIMMEL, Stephen R. DECKER, Jeffrey G. LINGER, Kara PODKAMINER, John O. BAKER, Larry TAYLOR, II, Qi XU, Arjun SINGH
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Abstract
Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in hosts such as fungi, which in turn may be cultured to produce chimeric polypeptides. Also disclosed are chimeric polypeptides and their use in the degradation of cellulosic materials.
Claims21
1-20. (canceled)
An isolated chimeric fungal Cel7A polypeptide, comprising a catalytic domain (CD), a carbohydrate-binding module (CBM) and a linker domain, wherein at least one of the domains is from a Penicillium funiculosum Cel7A polypeptide and at least one of the domains is from a Trichoderma reesei Cel7A polypeptide;
- and wherein each domain is from a fungal Cel7A polypeptide.
Dependencies are inferred from the claim text.