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US 2017/0247404 A1Published application
Process for the preparation of sofosbuvir
AssigneeHc-Pharma AG
InventorsMauro GABOARDI, Giuseppe PALLANZA, Marco BARATELLA, Graziano CASTALDI, Marta CASTALDI
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Abstract
The present invention relates to a process for the synthesis of Sofosbuvir.
Claims20
1) A process for the synthesis of Sofosbuvir of formula (I)
- comprising selectively mono-deacetylating a compound of formula (V)
- to obtain a compound of formula (IV)
16) The process according 15 wherein the temperature is from −10° C. to 10° C.
Dependencies are inferred from the claim text.