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US 2017/0247349 A1Published application
Synthesis of chirally enriched 2,4-disubstituted tetrahydropyran-4-ol and its derivatives
AssigneeS.H. Kelkar and Company Ltd.
InventorsSujata V. Bhat, Ravindra D. Gaikwad, Kedar R. Vaze
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Abstract
The present invention discloses a process for synthesis of chiral 2,4-disubstituted-tetrahydropyran-4-ol and its derivatives having a general formula (I) comprising of asymmetric reaction of an aliphatic aldehyde and a homoallylic alcohol in the presence of a chiral organocatalyst, and a fragrance and cosmetic composition containing chirally enriched molecules of the said general formula (I) prepared by the aforesaid process.
Claims10
A process for synthesis of chirally enriched 2,4-disubstituted-tetrahydropyran-4-ol and its derivatives having a general formal (I)
- comprising of reaction of an aliphatic aldehyde and a homoallylic alcohol in the presence of a chiral organocatalyst;
- wherein R2, R3 and R4 are selected from the groups consisting of hydrogen, methyl, ethyl, propyl, butyl, isopropyl, isobutyl, isobutenyl, acetyl or propionoyl.
(canceled)
Dependencies are inferred from the claim text.