Active Agent Delivery Devices and Methods of Using the Same
AssigneeThe Regents of the University of California
InventorsKiana Aran, Jacobo Paredes, Niren Murthy, Dorian Liepmann, Kunwoo Lee
Life of this patent
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Abstract
Provided are active agent delivery devices configured to deliver an active agent formulation into or through a mucosal layer in a subject. The active agent delivery devices include a power reservoir configured to eject the active agent formulation at a pressure sufficient to deliver the active agent formulation into or through a mucosal layer in a subject. Methods of using the subject active agent delivery devices are also provided.
Claims27
An active agent delivery device comprising:
- an active agent reservoir at an active agent reservoir end of the device configured to contain an active agent formulation;
- a power reservoir at a power reservoir end of the device configured to eject the active agent formulation at a pressure sufficient to deliver the active agent formulation into or through a mucosal layer in a subject;
- and
- a moveable separator separating the power reservoir from the active agent reservoir.
The active agent deliver device of any of the preceding claims, wherein the device comprises a valve separating the power reservoir from the exterior of the device.
The active agent delivery device of any of the preceding claims, wherein the active agent comprises a macromolecule.
The active agent delivery device of any of the preceding claims, wherein the active agent formulation comprises a liquid.
The active agent delivery device of any of the preceding claims, wherein the device comprises a tubular member having a planar surface at the active agent reservoir end and a hemispherical structure at the power reservoir end.
The active agent delivery device of any of the preceding claims, wherein the device is configured to promote contact of the active agent reservoir end with a mucosal surface in a subject.
Dependencies are inferred from the claim text.