Loading patent…
AssigneesYes, Inc., The Trustees of Columbia University in the City of New York
InventorsLinda Eastwood, Harold Coons, James M. Sinclair, Matthew D. Bacchetta, Gopal Singh
Estimating the term…
The present invention provides hemostatic compositions comprising components of the flowers of pharmaceutical chamomile (Chamomilla recutita), the leaves of dioecious nettle (Urtica dioica), kaolin, chitosan, fibrinogen and thrombin. Further inclusion of a biocompatible polymeric base, particularly an alignate, generates a composition with superior and broad spectrum hemostatic capabilities, including the ability to arrest arterial hemorrhage. The invention further provides methods of using the inventive compositions in to reduce or stop bleeding, as well as a variety of apparatuses useful in hemostatic contexts that incorporate the inventive compositions. In one particular embodiment, the invention provides hemostatic dressings in which a polymeric layer incorporating chamomile, nettle, kaolin, chitosan, fibrinogen and thrombin components is applied to a textile or fabric material, for example a non-woven viscose.
1-28. (canceled)
A method of preparing a hemostatic composition, the method comprising:
A method of preparation of a hemostatic composition, the method comprising:
A dressing for topical or transdermal administration comprising a hemostatic composition comprising a therapeutically effective amount of components including chamomile, dioecious nettle, kaolin, chitosan, fibrinogen, thrombin and a biocompatible polymer, wherein the kaolin:biocompatible polymer ratio by weight is 0.01-0.03:1, the chitosan:biocompatible polymer ratio by weight is 0.02-0.07:1, the fibrinogen:biocompatible polymer ratio by weight is 0.30-1.2:1, and the thrombin:biocompatible polymer ratio by weight is 0.03-0.08:1.
A method of controlling or lessening the severity of bleeding in a patient in need thereof, wherein said method comprises
A method of promoting wound healing in a patient in need thereof, wherein said method comprises
A method of treating a burn in a patient in need thereof, wherein said method comprises
Dependencies are inferred from the claim text.