Therapeutic agents and use thereof
AssigneeSwansea University
InventorsROBERT CONLAN, DEYARINA GONZALEZ
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Abstract
A therapeutic agent comprising a cell binding agent which binds the Receptor for Advanced Glycation End (RAGE) products linked to an anti-cancer drug, for use in the treatment of gynaecological cancer, endometriosis or polycystic ovary syndrome. Novel cell binding agents, pharmaceutical compositions and methods are also described and claimed.
Claims20
1-20. (canceled)
A method for treating a proliferative condition selected from gynaecological cancers, endometriosis or polycystic ovary syndrome, wherein the method comprises administering to a patient in need thereof an effective amount of a therapeutic agent comprising a cell binding agent which binds the Receptor for Advanced Glycation End products (RAGE) linked to an anti-cancer drug.
A cell binding agent which specifically binds to SEQ. ID. NO. 24, or to a V-region, or to a region for which MAB11451 binding is specific.
Dependencies are inferred from the claim text.