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US 2017/0246269 A1Published application
Methods of treating or preventing periodontitis and diseases associated with periodontitis
OwnerGeorgios Hajishengallis, John D. Lambrisinventors
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Abstract
The present disclosure describes methods for preventing or treating periodontitis or diseases associated with periodontitis. The present disclosure also describes methods of screening for compounds that can be used to prevent or treat periodontitis or diseases associated with periodontitis.
Claims13
A method of treating or preventing periodontitis or diseases associated with periodontitis in an individual, comprising:
- (a) identifying an individual suffering from or at risk of developing periondontitis or a disease associated with periodontitis;
- and (b) administering to the individual a complement inhibitor selected from C1 Inhibitor (C1-inh), Factor H, a Factor D inhibitor, or any combination thereof, thereby treating or preventing the periodontitis or diseases associated with periodontitis.
A method of reducing the amount of Porphyromonas gingivalis and/or the inflammation caused by P. gingivalis in an individual, comprising:
- (a) identifying an individual in which reduction in the amount of P. gingivalis is needed or desired, and (b) administering to the individual a complement inhibitor selected from C1 Inhibitor (C1-inh), Factor H, a Factor D inhibitor, or any combination thereof, thereby reducing the amount of P. gingivalis in the individual.
Dependencies are inferred from the claim text.