Methods of Using Interleukin-10 for Treating Diseases and Disorders
AssigneeArmo Biosciences, Inc.
InventorMartin OFT
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Abstract
Methods of treating subjects having a disease or disorder responsive to IL-10, including methods of administration and dosing regimens associated therewith, are provided.
Claims76
A method of treating or preventing a disease, disorder or condition in a subject, comprising administering to the subject a therapeutically effective amount of an IL-10 agent, wherein the amount is sufficient to achieve a mean IL-10 serum trough concentration of at least 6.0 ng/mL.
A method of treating or preventing a disease, disorder or condition in a subject, comprising administering to the subject a therapeutically effective amount of an IL-10 agent, wherein the amount is sufficient to maintain a mean IL-10 serum trough concentration over a period of time;
- wherein the mean IL-10 serum trough concentration is at least 6.0 ng/mL, and
- wherein the mean IL-10 serum trough concentration is maintained for at least 90% of the period of time.
A method of treating or preventing a disease, disorder or condition in a subject, comprising administering to the subject a therapeutically effective amount of an IL-10 agent, wherein the amount is sufficient to achieve a mean IL-10 serum trough concentration of at least the EC50 of the IL-10 agent.
Dependencies are inferred from the claim text.