Neurokinin 1 receptor agonist mediated protection of the eye
AssigneeWayne State University
InventorsSusmit Suvas, Subhash Gaddipati
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Abstract
Neurokinin 1 receptor (NK1R) agonist mediated protection of the eye is described. The protection can reduce dry eye and ocular infections, particularly in individuals with reduced NK1R activity.
Claims20
A method of protecting the eye in a subject in need thereof comprising administering a therapeutically effective amount of an NK1R agonist to the subject thereby protecting the eye in the subject in need thereof.
A method of reducing dry eye and ocular infections in a subject in need thereof comprising administering a therapeutically effective amount of a Neurokinin 1 Receptor (NK1R) agonist to the subject thereby reducing dry eye and ocular infections in the subject in need thereof.
A topical ophthalmic formulation comprising an NK1R agonist selected from SEQ ID NOs. 2-6.
Dependencies are inferred from the claim text.