Inhibitors of Bruton's Tyrosine Kinase for the Treatment of Solid Tumors
AssigneePharmacyclics, Inc.
InventorsLee Honigberg, Erik J. Verner, Joseph J. Buggy, David J. Loury, Wei Chen
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Abstract
Described herein are irreversible Btk inhibitor compounds, and methods for using such irreversible inhibitors in the treatment of diseases and disorders characterized by the presence or development of solid tumors.
Claims11
-26. (canceled)
A method for treating a solid tumor in a subject comprising administering to the subject having solid tumor, a compound having the structure:
- or a pharmaceutically acceptable salt thereof, wherein the solid tumor is selected from colon cancer, breast cancer, and non-small cell lung cancer.
A method for treating colon cancer in a subject comprising administering to the subject having colon cancer, a compound having the structure:
- or a pharmaceutically acceptable salt thereof.
A method for treating colon cancer in a subject comprising administering to the subject having colon cancer, a compound having the structure:
Dependencies are inferred from the claim text.