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US 2017/0246117 A1Published application
Injectable microparticles for hyper-localized release of therapeutic agents
OwnerJames A. Helliwell, Amanda M. Maloneinventors
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Abstract
Described herein are injectable drug-loaded microparticles, pharmaceutical composition thereof and methods for using the same in a body compartment or for systemic administration.
Claims19
A pharmaceutical composition, comprising:
- a plurality of microparticles, the microparticle including:
- (1) a drug core of more than 90% by weight of the microparticle, the drug core including one or more therapeutic agents selected from an anesthetic, an antibiotic agent, a central nerve system (CNS) agent, or a chemotherapeutic agent;
- and
- (2) a polymeric shell encapsulating the drug core, the polymeric shell being in contact but immiscible with the drug core, wherein the plurality of microparticles have a mean diameter in the range of 80 μm to 150 μm and a standard deviation of less than 50% of the mean diameter.
1 more element
Dependencies are inferred from the claim text.