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OwnerRoey Jacob AMIR, Marina BUZHOR +3inventors
InventorsRoey Jacob AMIR, Marina BUZHOR, Assaf Josef HARNOY, Ido ROSENBAUM, Liat FRID
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The present invention relates to an amphiphilic hybrid delivery system in micellar form for delivery of agrochemicals, based on a hydrophilic polyethylene glycol (PEG) polymer conjugated to a hydrophobic dendron, the dendron comprising at least one pH-dependent or enzymatically cleavable hydrophobic end group that is covalently attached to the dendron, wherein the micelle disassembles upon enzymatic or pH-dependent cleavage of the hydrophobic end group. The hydrophobic end group that is conjugated to the dendron may comprise an agrochemical, and/or the micelle may (non-covalently) encapsulate an agrochemical. The present invention further provides methods of use thereof and to a kit comprising same.
1-47. (canceled)
An amphiphilic hybrid delivery system in micellar form for the delivery of agrochemicals, comprising a hydrophilic polyethylene glycol (PEG) polymer conjugated to a hydrophobic dendron, the dendron comprising at least one enzymatically or pH-dependent cleavable hydrophobic end group that is covalently attached to the dendron, wherein said micelle comprises an agrochemical either as part of the hydrophobic end group, or encapsulated within the micelle, or both, and wherein said micelle disassembles to release the agrochemical upon enzymatic or pH-dependent cleavage of said hydrophobic end group.
Dependencies are inferred from the claim text.