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US 2017/0241946 A1Published application
Devices and Methods using Pore Size Modulation for Detecting Analytes in a Fluid Sample
AssigneeThe Regents of the University of Calfornia
InventorsAmy E. Herr, Todd A. Duncombe
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Abstract
Provided are devices that include a polymeric separation medium configured to immobilize one or more constituents of interest in the polymeric separation medium and have an increased pore size upon application of an applied stimulus. Systems including the devices, as well as methods of using the devices, are also provided. Embodiments of the present disclosure find use in a variety of different applications, including detecting whether an analyte is present in a fluid sample.
Claims26
A device comprising:
- a polymeric separation medium that immobilizes one or more constituents of interest in the polymeric separation medium and has an increased pore size upon application of an applied stimulus.
A method of detecting an analyte in a fluid sample, the method comprising:
- introducing a fluid sample into a device comprising a polymeric separation medium that immobilizes one or more constituents of interest in the polymeric separation medium and has an increased pore size upon application of an applied stimulus;
- applying an electric field across the polymeric separation medium in a manner sufficient to separate components of the fluid sample in the polymeric separation medium to provide a separated sample;
- and
- detecting the analyte in the separated sample.
1 more element
Dependencies are inferred from the claim text.