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US 2017/0217908 A1Published application
Benzotriazine Oxides as Drugs Targeting Mycobacterium Tuberculosis
AssigneeSRI International
InventorsPeter Madrid, Sidharth Chopra, Kenneth Ryan, Gary Koolpe
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Abstract
Benzotriazine doxides are disclosed as drugs targeting mycobacterium tuberculosis, including novel compounds of formula I:
Claims10
A compound having the structure of formula I:
- wherein:
- each X is independently H, halogen, alkyl, OR, SR, NR′R, or BR′R, wherein each R and each R′ is independently H, halogen, or alkyl;
- W is N;
- each A and B is optionally substituted alkyl, or A and B are joined in an optionally substituted heterocycloalkyl;
- and
- Z is an optionally present, optionally substituted 5 or 6-membered ring, saturated or unsaturated, fused to the bezotriazine ring at the 6,7 position,
- or a pharmaceutically acceptable salt or stereoisomer thereof.
4 more elements
Dependencies are inferred from the claim text.