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US 2017/0204443 A1Published application
Biotechnological production of lnt, lnnt and the fucosylated derivatives thereof
AssigneeBASF SE
InventorsFlorian BAUMGÄRTNER, Georg A. SPRENGER, Christoph ALBERMANN
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Abstract
The present invention relates to primarily genetically modified microorganisms for in vivo synthesis of lacto-N-tetrose (LNT) and lacto-N-neotetrose (LNnT), and their fucosylated derivatives, and to uses of such microorganisms in methods of producing lacto-N-tetrose and lacto-N-neotetrose, and their fucosylated derivatives.
Claims21
1-17. (canceled)
A genetically modified microorganism for in vivo synthesis of lacto-N-tetrose or lacto-N-neotetrose, said microorganism comprising:
- (i) a first transgene coding for β1,3-N-acetylglucosaminyltransferase;
- and
- (ii) a second transgene coding for β1,3-galactosyltransferase or β1,4-galactosyltransferase.
Dependencies are inferred from the claim text.