Transgenic algae for delivering antigens to an animal
AssigneesSolarvest Bioenergy Inc., The Ohio State University
InventorsRichard T. SAYRE, Richard E. WAGNER, Surasak SIRIPORNADULSIL, Carlos FARIAS
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Abstract
Delivery systems and methods are provided for delivering a biologically active protein to a host animal. The systems and methods provided include obtaining an algal cell transformed by an expression vector, the expression vector comprising a nucleotide sequence coding for the biologically active protein, operably linked to a promoter. In one illustrated embodiment, the biologically active protein is an antigenic epitope and upon administration to the animal the algal cell induces an immune response in the host animal.
Claims5
A method for inducing an immune response in an animal, comprising the steps of
- obtaining a transgenic alga expressing an antigenic peptide, wherein the antigenic peptide is at least partially derived from a microorganism that is pathogenic to the animal, and
- administering the transgenic alga to the animal, wherein the transgenic alga is administered in a dosage effective for inducing an immune response, and wherein the transgenic alga induces an immune response in the animal.
Dependencies are inferred from the claim text.