Polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer
AssigneeColorado State University Research Foundation
InventorsSusan P. JAMES, Susan S. YONEMURA, Ariane VARTANIAN
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Abstract
The present invention relates to polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer. The present invention also relates to hydrogels containing the polymeric materials. The present invention further relates to methods of synthesizing the polymeric materials and hydrogels of the present invention.
Claims20
A polymeric material comprising a tripolymer glycosaminoglycan-polyolefin network, wherein said tripolymer glycosaminoglycan-polyolefin network is synthesized by reacting a first constituent, a second constituent, and a third constituent with one another in a single phase,
- wherein said first constituent comprises a modified glycosaminoglycan,
- wherein said second constituent comprises an alternating copolymer of a polyolefin with an acid anhydride,
- wherein said third constituent comprises a graft copolymer having a polyolefin backbone functionalized/grafted with an acid anhydride, and
- wherein the first constituent, the second constituent, and the third constituent react to form covalent bonds.
A method of synthesizing a polymeric material comprising a tripolymer glycosaminoglycan-polyolefin network, said method comprising:
- providing the following constituents:
- (1) a first constituent comprising a modified glycosaminoglycan;
- (ii) a second constituent comprising an alternating copolymer of a polyolefin with an acid anhydride;
- and
- (iii) a third constituent comprising a graft copolymer having a polyolefin backbone functionalized/grafted with an acid anhydride;
- and
- reacting the first constituent, the second constituent, and the third constituent under conditions effective to yield a tripolymer glycosaminoglycan-polyolefin network,
- wherein said tripolymer glycosaminoglycan-polyolefin network comprises the first constituent, the second constituent, and the third constituent covalently bound to one another.
Dependencies are inferred from the claim text.