Clathrin replacement therapeutics
OwnerFranco Vitaliano, Gordana Dragan Vitalianoinventors
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Abstract
The invention in suitable embodiments is directed to replacement therapeutics. In one aspect, a medicament is comprised in whole or in part of one or more clathrin heavy chain protein that is formed from a plurality of isolated, synthetic or recombinant clathrin protein molecules. In one embodiment, a man-made clathrin heavy chain protein composition replaces and/or modifies cell elements or processes, in vivo or in vitro, thereby treating a disease, condition, or disorder comprising at least one of cell.
Claims26
A pharmaceutical composition for replacement therapy comprising:
- a man-made non-cage clathrin heavy chain protein that has an amino acid sequence of at least 50, 60, 70, 80, or 90% sequence identity when compared to SEQ ID NO:
- 1, and administering to a subject in need thereof the preceding protein or composition, and the protein or composition is taken up in whole or in part by a living cell in vivo or in vitro, wherein the protein or composition replaces and/or modifies at least one of cell element or process, and treats a disease, condition, or disorder comprising at least one of cell.
A method for a pharmaceutical composition for replacement therapy comprising:
- forming pharmaceutical composition for replacement therapy comprising:
- a man-made non-cage clathrin heavy chain protein that has an amino acid sequence of at least 50, 60, 70, 80, or 90% sequence identity when compared to SEQ ID NO:
- 1, and administering to a subject in need thereof the preceding protein or composition, and the protein or composition is taken up in whole or in part by a living cell in vivo or in vitro, wherein the protein or composition replaces and/or modifies at least one of cell element or process, and treats a disease, condition, or disorder comprising at least one of cell.
Dependencies are inferred from the claim text.