Methods for determining gene-nutrient interactions
AssigneeBodysync, Inc.
InventorsRosalynn D. GILL, Keith A. GRIMALDI
Life of this patent
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Abstract
The present invention provides methods and tests that allow for the establishment of personalized weight-management programs for an individual based upon the individual's genotype in the glutathione S-transferase pi gene and/or the interleukin-6 gene. Methods are disclosed for determining the individual's genotype, which may be used to select an appropriate therapeutic/dietary program or lifestyle recommendation. Such a personalized weight-management program will have obvious benefits (e.g., yield better results in terms of weight loss and weight maintenance) over traditional weight-management programs that do not take into account genetic information.
Claims19
A method for selecting a weight loss program for an individual comprising
- a. determining the individual's GSTP1 genotype at loci position 313, 341 or both;
- b. selecting a weight loss program for the individual when the individual comprises a genotype selected from the group consisting of homozygous for the G allele at position 313, heterozygous (A/G) at position 313, homozygous for the T allele at position 341, heterozygous (C/T) at position 341, and combinations thereof wherein the weight loss program is modified from a weight loss program for a comparable individual who is wild-type at positions 313 and 341.
A method for selecting a dietary plan for an individual in need of achieving an increase in body weight, the method comprising
- a. determining the individual's GSTP1 genotype at loci position 313 of the GSTP1 gene;
- b. selecting a dietary program for the individual when the individual comprises a genotype comprising homozygous for the A allele at position 313, wherein the dietary program recommends a lower calcium intake compared to a dietary program for an individual who is not in need of achieving an increase in body weight.
A method for selecting a weight loss program for an individual under the age of 50, comprising
- a. determining the individual's IL-6 genotype at loci position −174;
- b. selecting a weight loss program for the individual when the individual comprises a genotype selected from the group consisting of homozygous for the G allele at position −174 and heterozygous (C/G) at position −174, wherein the weight loss program is modified from a weight loss program for a comparable individual who is homozygous for the C allele at position −174.
Dependencies are inferred from the claim text.