Composition including Stem Cell-Derived Exosome for Inducing Adipogenic Differentiation and Adipose Tissue Regeneration
AssigneeExostemtech Co., Ltd.
InventorsYong Woo CHO, Ji Suk CHOI, Seong Hyun YANG, Kyoung-Soo LEE, Eun Ji KIM, Hwa In YOON, Jun Sung KIM
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Abstract
A composition for inducing differentiation into adipocytes or regenerating adipose tissues comprises, as an ingredient, exosomes derived from stem cells differentiating into adipocytes, or exosomes derived from proliferating stem cells.
Claims22
A composition for inducing differentiation into adipocytes or regenerating adipose tissues comprising, as an ingredient, exosomes derived from stem cells differentiating into adipocytes.
A method of inducing stem cells differentiating into adipocytes, the method comprising:
- preparing exosomes derived from the stem cells differentiating into adipocytes;
- and
- treating stem cells with the exosomes for a time period.
A method of inducing adipose tissue regeneration using exosomes, the method comprising:
- preparing exosomes derived from stem cells differentiating into adipocytes;
- placing the exosomes in a supporting material;
- and
- administering the supporting material to a subject, thereby regenerating adipose tissues, the supporting material including a hydrogel.
A method of producing a composition containing exosomes, the method comprising:
- preparing exosomes derived from stem cells differentiating into adipocytes;
- and
- mixing the exosomes with one or more of stearic acid, cetyl alcohol, lanolin alcohol, liquid paraffin, Cyclomethicone, polyoxyethylene monoolein acid ester hexanediol, glycerin, triethylamine, and carbomer.
Dependencies are inferred from the claim text.