Method of producing terpenes or terpenoids
AssigneeDeinove
InventorsNICOLAS CHABOT, SANDRA CASTANG, PHILIPPE BAUCHART, JEAN-PAUL LEONETTI
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Abstract
The present invention relates to a recombinant Deinococcus bacterium exhibiting enhanced 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate (MEP/DXP) pathway, and its use for producing terpene or terpenoid compounds.
Claims23
1-22. (canceled)
A method of producing a terpene or terpenoid comprising (i) culturing a recombinant Deinococcus bacterium that is genetically modified to increase 1-deoxyxylulose 5-phosphate synthase (DXS) activity and/or isopentenyl pyrophosphatase isomerase (IPP isomerase) activity, under conditions suitable to produce the terpene or terpenoid and optionally (ii) recovering the terpene or terpenoid.
A recombinant Deinococcus bacterium comprising genetic modifications that increase 1-deoxyxylulose 5-phosphate synthase (DXS) activity and/or isopentenyl pyrophosphatase isomerase (IPP isomerase) activity.
Dependencies are inferred from the claim text.