Nutritional compositions comprising a lipophilic active ingredient
AssigneeAbbott Laboratories
InventorsPAUL JOHNS, MUSTAFA VURMA, STEPHEN DEMICHELE, GARY KATZ
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Abstract
Disclosed embodiments provide methods and compositions for improving the metabolic health of consumers. Bovine beta-casein, a major component of milk from cattle, has many genetic variants. Certain genetic variants, A1 in particular, have been associated with type 1 diabetes. The disclosed methods and compositions include reduced amounts of genetic variants of beta-casein that have been associated with diabetes. In some embodiments, the compositions display improved emulsions due to the solubility and hydrophobicity of the genetic variants of beta-casein used therein.
Claims25
A shelf stable nutritional composition comprising:
- protein comprising 10% to 100% bovine beta-casein, the bovine beta-casein comprising 50% to 100% genetic variant A2;
- and
- a lipophilic nutrient selected from the group comprising vitamin A, vitamin D, and vitamin E;
- wherein the molar ratio of the A2 bovine beta-casein to the lipophilic nutrient is 10:1 to 10,000:1.
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A liquid nutritional composition with improved lipophilic nutrient stability, the nutritional composition comprising:
- carbohydrate;
- protein comprising 10% to 100% bovine beta-casein, wherein the bovine beta-casein is 50% to 100% genetic variant A2;
- fat;
- and
- a premix comprising monoglyceride and diglyceride oil, and a lipophilic nutrient;
- wherein the nutritional composition is formed by adding the premix to an aqueous solution to form an activated premix, and adding the activated premix to the nutritional composition.
A method for preparing a nutritional composition comprising a lipophilic nutrient having improved bioavailability, the method comprising:
- providing a premix comprising monoglycerides, diglycerides, and a lipophilic nutrient;
- adding the premix to an aqueous solution to form an activated premix;
- and
- adding the activated premix to the nutritional composition;
- wherein the nutritional composition comprises bovine beta-casein in an amount of 10% to 100% by weight of the total protein in the composition, the bovine beta-casein comprising 50% to 100% genetic variant A2.
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Dependencies are inferred from the claim text.