Methods and compositions for cytometric detection of circulating tumor cell markers in a sample
OwnerMargaret Inokumainventor
Life of this patent
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Abstract
Methods of determining whether a circulating tumor cell (CTC) marker, e.g., a CTC or fragment thereof, is present in a sample, such as a blood sample, are provided. Aspects of the methods include flow cytometrically assaying a fluorescently labeled sample that has been fluorescently labeled with a fluorescently labeled chlorotoxin binding member to determine whether a CTC marker is present in the sample. Also provided are compositions for practicing the methods. The methods and compositions find use in a variety of applications.
Claims25
A method of determining whether a circulating tumor cell (CTC) marker is present in a sample, the method comprising:
- flow cytometrically assaying a fluorescently labeled sample that has been fluorescently labeled with a fluorescently labeled chlorotoxin binding member to determine whether a CTC marker is present in the blood sample.
5-7. (canceled)
11-12. (canceled)
A fluorescently labeled sample that has been fluorescently labeled with a fluorescently labeled chlorotoxin binding member.
23-31. (canceled)
(canceled)
A kit for identifying a CTC marker in a sample, the kit comprising:
- a container configured to receive an amount of a sample;
- and
- a fluorescently labeled chlorotoxin binding member.
36-42. (canceled)
Dependencies are inferred from the claim text.