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US 2017/0029853 A1Published application
Acid-tolerant yeast cell, method of producing organic acid using the same, and method of producing the yeast cell
AssigneeSamsung Electronics Co., Ltd.
InventorsHunsu Chu, Hwayoung Cho, Jinhwan Park, Dongsik Yang, Hongsoon Rhee, Kwangmyung Cho
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Abstract
Provided is an acid-tolerant yeast cell, a method of producing an organic acid by using the yeast cell, and a method of producing the yeast cell resistant to acid.
Claims20
An acid-tolerant genetically engineered yeast cell comprising
- a genetic modification that increases activity of an enzyme that catalyzes conversion of phosphatidylinositol (PI) and ceramide to inositol phosphorylceramide (IPC) and diacylglycerol (DG);
- a genetic modification that increases activity of an enzyme, which catalyzes introduction of a double bond to a fatty acyl site of a fatty acyl-CoA;
- a genetic modification that decreases activity of an enzyme, which catalyzes formation of triacylglycerol (TG) from diacylglycerol (DG) or
- a combination of the genetic modifications.
1 more element
Dependencies are inferred from the claim text.