Nutritional compositions containing phosphatidylethanolamine, sphingomyelin and docosahexaenoic acid
AssigneeMead Johnson Nutrition Company
InventorsChenzhong Kuang, Dirk Hondmann, Robert J. McMahon, Yan Xiao
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Abstract
The present disclosure provides a composition and method for promoting functional neuronal development in pediatric subjects. The composition comprises in some embodiments up to about 7 g/100 Kcal of a fat or lipid source; up to about 5 g/100 Kcal of a protein source; about 3 mg/100 Kcal to about 50 mg/100 Kcal of phosphatidylethanolamine; about 0.15 mg/100 Kcal to about 75 mg/100 Kcal of sphingomyelin; and about 5 mg/100 Kcal to about 75 mg/100 Kcal of docosahexaenoic acid. The methods comprise, in some embodiments, administering the aforementioned composition to a pediatric subject.
Claims20
A nutritional composition for promoting neuronal maturation in a pediatric subject, comprising:
- up to about 7 g/100 Kcal of a fat or lipid;
- up to about 5 g/100 Kcal of a protein source;
- about 3 mg/100 Kcal to about 50 mg/100 Kcal of phosphatidylethanolamine;
- about 0.15 mg/100 Kcal to about 75 mg/100 Kcal of sphingomyelin;
- and
- about 5 mg/100 Kcal to about 75 mg/100 Kcal of docosahexaenoic acid.
The composition of claim 11, wherein polydextrose and galactooligosaccharides comprise at least about 20% of the prebiotic composition.
A method for promoting neuronal maturation in a pediatric subject, the method comprising administering to the pediatric subject a nutritional composition comprising:
- up to about 7 g/100 Kcal of a fat or lipid source;
- up to about 5 g/100 Kcal of a protein source;
- about 3 mg/100 Kcal to about 50 mg/100 Kcal of phosphatidylethanolamine;
- about 0.15 mg/100 Kcal to about 75 mg/100 Kcal of sphingomyelin;
- about 10 mg/100 Kcal to about 200 mg/100 Kcal of lactoferrin;
- and
- about 5 mg/100 Kcal to about 75 mg/100 Kcal of docosahexaenoic acid.
A maternal nutritional supplement comprising:
- phosphatidylethanolamine;
- sphingomyelin;
- lactoferrin;
- and
- docosahexaenoic acid.
A method for promoting neuronal maturation in a fetus comprising
- administering to a female subject pregnant with the fetus a maternal nutritional supplement comprising:
- phosphatidylethanolamine;
- sphingomyelin;
- lactoferrin;
- and
- docosahexaenoic acid.
A method for promoting neuronal maturation in an infant comprising
- a) administering to a lactating female subject a nutritional supplement comprising:
- phosphatidylethanolamine;
- sphingomyelin;
- lactoferrin;
- and
- docosahexaenoic acid.
- b) administering breast milk from the lactating female to the infant.
Dependencies are inferred from the claim text.