Compositions and methods for preparation of poorly water soluble drugs with increased stability
AssigneeAbraxis BioScience, LLC
InventorsTapas DE, Neil P. DESAI, Andrew YANG, Zachary YIM, Patrick SOON-SHIONG
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Abstract
The present invention provides stable pharmaceutical compositions of poorly water soluble pharmaceutical agents and stabilizing agents which function to increase stability of the compositions. The use of stabilizing agents provide extended stability of nanoparticle suspensions and other formulations of poorly water soluble pharmaceutical agents such as docetaxel under certain conditions, for example upon dilution for administration.
Claims21
A composition comprising docetaxel and a stabilizing agent, wherein stability of the composition is enhanced as compared to that of a composition without the stabilizing agent.
21-36. (canceled)
Dependencies are inferred from the claim text.