Polyphosphazene delivery system for inorganic nanocrystals
AssigneeThe Trustees of the University of Pennsylvania
InventorsDAVID PETER CORMODE, PETER CHHOUR, ANDREW TSOURKAS, HARRY ALLCOCK, REBE'E CHEHELTANI
Life of this patent
Estimating the term…
Abstract
Nanoclusters comprising inorganic nanocrystals and a biodegradable polymer are disclosed. The inorganic nanocrystals have a mean particle size of 1 to 500 nm. The inorganic nanocrystals are contained within a core of the nanoclusters, on the surface of the nanoclusters, contained within a core of the nanoclusters, dispersed throughout the nanoclusters, or a combination thereof. The biodegradable polymer allows the inorganic nanocrystals to be excreted renally over a period of time. The nanoclusters can be used for medical imaging or other biomedical applications.
Claims28
A nanocluster comprising:
- a plurality of inorganic nanocrystals;
- a biodegradable polymer;
- wherein the plurality of inorganic nanocrystals are contained on a surface of the nanocluster, within a core of the nanocluster, dispersed throughout the nanocluster, or a combination thereof.
Dependencies are inferred from the claim text.