Device and method of personalized medicine

A method for the treatment of a first patient comprising the steps of:

• accepting a first xenograft from a first location in the first patient comprising cells of a first neoplasm;
• placing in a vivarium a first set of animals in one or more cages;
• subdividing the first set of animals into one or more subsets;
• identifying a negative phenotype;
• wherein the negative phenotype comprises behaviors and physiological indicators that are consistent with the first set of animals receiving no placement of cells of the first xenograft and no therapeutic treatment;
• placing at least a portion of the first xenograft in a first location in the brain of each animal (a “subject animal”) in the one or more subsets of animals;
• wherein the first location in the brain is associated with a first known set of animal behaviors;
• identifying a positive phenotype, wherein the positive phenotype comprises behaviors and physiological indicators that are compatible unhealthy functioning of the first location of the first organ of the first set of animals;
• treating each of the one or more subsets with an associated treatment regimen, wherein the associated treatment regimen for each subset is unique;
• aggregating, measuring and timing one or more phenotype of the one or more subsets of animals, the “treatment phenotypes”;
• comparing the treatment phenotypes of each one or more subsets to both the negative baseline phenotype and the positive baseline phenotype;
• selecting a regimen responsive to some combination of:
• (a) (the least difference between the treatment phenotype and the negative baseline phenotype) and (b) (the largest difference between the treatment phenotype and the set of positive baseline phenotype), for each associated treatment phenotype associated with the regimen;
• and
• treating the first patient with the selected regimen.