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US 2017/0000882 A1Published application
Genetically Detoxified Pertussis Vaccine that Maintains Intrinsic Adjuvant Activity
AssigneeInventprise, LLC
InventorSubhash V. Kapre
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Abstract
The invention is directed to a method for the production of a pertussis vaccine and, in particular, a detoxified pertussis vaccine comprising detoxified pertussis toxin (PT), detoxified pertussis lipopolysaccharide (P-LPS), and detoxified pertussis adenylate cyclase toxin (P-ACT). The invention is also directed to the manufacture of a vaccine or the invention and methods for the administration of a detoxified vaccine to patients.
Claims20
A vaccine for the treatment or prevention of an infection in a mammal comprising:
- a detoxified pertussis toxin protein;
- an enzyme treated pertussis LPS;
- and
- a detoxified pertussis adenylate cyclase protein.
1 more element
Dependencies are inferred from the claim text.