Toxoid preparation and uses thereof
AssigneeArytha Biosciences, LLC
InventorChe-Ming Jack HU
Life of this patent
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Abstract
The present invention relates to toxoid preparations comprising a non-disrupted and/or a non-denatured toxin associated with a particulate vector that minimizes or precludes said toxin from inflicting damage at an action site of said toxin. The present invention also relates to immunogenic compositions or vaccines comprising the toxoid preparations, and the methods of using the toxoid preparations, immunogenic compositions or vaccines.
Claims26
A toxoid preparation, comprising a non-disrupted and/or a non-denatured toxin associated with a particulate vector that minimizes or precludes said toxin from inflicting damage at an action site of said toxin, provided that said toxoid preparation does not comprise a nanoparticle comprising an inner core comprising a non-cellular material, and an outer surface comprising a cellular membrane derived from a cell and a cell membrane inserting toxin, wherein said cell membrane inserting toxin is associated with said cellular membrane without a linker.
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