Romidepsin formulations and uses thereof
AssigneeCelgene Corporation
InventorsLianfeng HUANG, Ho-Wah HUI, Vijay NARINGREKAR, Gang YANG
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Abstract
Provided herein are liquid concentrate formulations of romidepsin. Also provided are methods for producing these formulations and uses thereof. In one embodiment, the formulation comprises romidepsin, polyethylene glycol, etanol and a citrate buffer. In another embodiment, the formulation comprises romidepsin, polyethylene glycol, etanol and an acetate buffer.
Claims21
1-17. (canceled)
A method of treating cancer in a subject comprising administering to the subject a formulation comprising romidepsin in a concentration of 1 mg/mL to 10 mg/mL, propylene glycol (PG), ethanol (EtOH) and an acetate buffer.
Dependencies are inferred from the claim text.