Method based on bismuth ion for the treatment and prevention of a disease caused by a shiga toxin
AssigneeSoubeiran Chobet S.R.L.
InventorHector Manuel Fernandez
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Abstract
The present invention relates to the a bismuth-based composition, particularly involving the use of bismuth ions, particularly the Bi+3 ion, for prevention and/or treatment of the haemolytic uremic syndrome, with the invention also relating to the use of a bismuth ion in the manufacture of a medicament for the prevention and/or treatment of an infection caused by a Shiga-toxin producing Escherichia coli strain, as well as to a method for preventing and/or treating the haemolytic uremic syndrome comprising administering bismuth ions to a patient in need thereof, and a method for inhibiting dissemination of the gene encoding virulence factors of a Shiga-toxin producing Escherichia coli strain in animals and humans.
Claims20
A treatment method for human hemolytic uremic syndrome caused by bacteria producing Shiga toxin, comprising the administration of a dose of a bismuth ion or any of its salts at a time of every 4 to 6 hours upon a first production of a diarrhea in the human.
A prophylactic treatment method for a patient having hemolytic uremic syndrome caused by bacteria producing Shiga toxin, comprising the administration of a prophylactically effective amount of bismuth or any of its salts to a patient in need thereof due to exposure to bacteria producing Shiga toxin.
A method of reducing Shiga toxin Escherichia coli fecal excretion in cattle in need thereof comprising administering an effective amount of bismuth ion or any of its salts to the cattle.
Dependencies are inferred from the claim text.