Methods of Treating Tumoral Diseases, or Bacterial or Viral Infections

A method of treating a mammal suffering from a tumoral disease, a bacterial infection, or a viral infection which comprises administering to the mammal a compound of Formula (I) or a pharmaceutically acceptable salt thereof.

• wherein:
• A and B are independently selected from absent, H or a moiety of Formula (II), with the proviso that at least one of A and B is a moiety of Formula (II);
• wherein:
• R and R1 are each independently selected from H, alkenyl, alkynyl, alkoxy, aryl, heteroaryl, C1-C8 alkyl or C3-C7 cycloalkyl, wherein in each of the C1-C8 alkyl or C3-C7 cycloalkyl optionally up to three carbon atoms are replaced by a heteroatom group independently selected from O, NR4, S, SO or SO2 (thereby making a heteroalkyl or heterocyclyl substituent), and wherein said C1-C8 alkyl and C3-C7 cycloalkyl are optionally substituted with from 1 to 4 C1-C8 alkyl, alkoxy, aryl or heteroaryl substituents;
• or R and R1 taken together with the atom to which they are attached form a 3- to 7-membered ring, wherein said 3- to 7-membered ring optionally contains up to two heteroatom groups selected from O, N R4, S, SO or SO2, and is optionally substituted with 1 to 4 alkoxy, F or Cl substituents;
• Y, independently for each occurrence, is selected from R2, OR2, NH2, NHR2, or NR2R3;
• R2 is selected from alkoxy, aryl, heteroaryl, C1-C8 alkyl or C3-C7 cycloalklyl, wherein in each of the C1-C8 alkyl or C3-C7 cycloalkyl optionally up to three carbon atoms are replaced by a heteroatom group independently selected from O, NR4, S, SO or SO2 (thereby making a heteroalkyl or heterocyclyl substituent), and wherein said C1-C8 alkyl and C3-C7 cycloalkyl are each optionally substituted with from 1 to 4 C1-C8 alkyl, alkoxy, aryl or heteroaryl substituents;
• R3 is selected from alkoxy, aryl, heteroaryl, C1-C8 alkyl or C3-C7 cycloalkyl, wherein in each of the C1-C8 alkyl or C3-C7 cycloalkyl optionally up to three carbon atoms are replaced by a heteroatom group independently selected from O, NR4, S, SO or SO2 (thereby making a heteroalkyl or heterocyclyl substituent and wherein said C1-C8 alklyl and C3-C7 cycloalklyl are each ostionally substituted with from 1 to 4 C1-C8 alkyl, alkoxy, aryl or heteroaryl;
• or
• R2 and R3 may be taken together with the nitrogen atom to which they are attached to form a 3- to 7-membered ring, wherein said 3- to 7-membered ring optionally contains up to three heteroatom groups selected from O, NR4 S, SO or SO2, and is o stionall substituted with alkoxy, F or Cl;
• R4 is, independently for each occurrence, selected from H or C1-C8 alkyl;
• and
• X and X1 are, each independently, an anion or absent, provided that X is absent only when A is absent, and X1 is absent only when B is absent.