Inhibitors of the fkbp51 protein from a high-throughput drug screen and methods of use
AssigneeUniversity of South Florida
InventorsJONATHAN JACOB SABBAGH, CHAD DICKEY
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Abstract
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.
Claims24
A method for treating a person or animal having a neurodegenerative disease or condition, or depression, a stress disorder, and/or an anxiety disorder, the method comprising administering to the person or animal a therapeutically effective amount of one or more compounds or drugs, or a composition comprising said one or more compounds or drugs, that inhibits FKBP51 activity or function.
Dependencies are inferred from the claim text.