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US 2017/0000774 A1Published application
Myeloid differentiation inducing agents
AssigneeCase Western Reserve University
InventorDavid Wald
Life of this patent
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Abstract
Myeloid differentiating agents can be used in the treatment of myeloid proliferative disorders.
Claims19
A method of inducing myeloid differentiation in a subject comprising:
- administering to the subject a therapeutically effective amount of at least one of securinine or a securinine analogue.
A method of treating acute myeloid leukemia in a subject, the method comprising:
- administering to the subject a therapeutically effective amount of at least one of securinine or a securinine analogue.
A method of treating a myeloid proliferative disorder in a subject, the method comprising:
- administering to the subject a therapeutically effective amount of at least one of securinine or a securinine analogue.
The method of claim 18, further comprising:
- administering an anti-proliferative agent in combination with the securinine or securinine analogue.
Dependencies are inferred from the claim text.