Back to results
US 2017/0000715 A1Published application
Pegylated 7-dehydrocholesterol derivatives
AssigneeHumedix Co., Ltd.
InventorsBong Youl CHUNG, Sung Sik BANG, Min Ji YOO, Myung Su KIM, Min Wook JEONG, In Wha JEONG, Yong Soo KIM
Life of this patent
Estimating the term…
Abstract
The present invention relates to pegylated 7-dehydrocholesterol derivatives, and a composition for wrinkle alleviation and anti-aging comprising the same. The pegylated 7-dehydrocholesterol derivatives according to the present invention have improved stability and solubility in water, and thus can be effectively used as a good source for supplying vitamin D in a cosmetic composition, a pharmaceutical composition and a functional food for wrinkle alleviation and anti-aging.
Claims16
A pegylated 7-dehydrocholesterol derivative of formula (I):
- wherein,
- R is hydrogen or C1-C6 alkyl,
- G is —XCOCH2(CH2)mCO—, —XCH2(CH2)mCO—, —XCONHCYCO—, —XCOCYNHCO(CH2)mCH2CO— or —XCH2(CH2)mCONHCYCO—,
- X is O, NH or S,
- Y is hydrogen, C1-C6 alkyl, (CH2)m′CH2NHCO(CH2)mCH2(OCH2CH2)nOR, (CH2)m′CH2NHCOCH2(CH2)mCO(OCH2CH2)nOR or (CH2)m′CH2NHCOCH2(CH2)mCO-DHC,
- n is an integer of 1 to 700, and
- m and m′ are each independently an integer of 1 to 3.
4 more elements
Dependencies are inferred from the claim text.