Osteoconductive and osteoinductive implant for augmentation, stabilization, or defect reconstruction
AssigneeUniversity of South Florida
InventorsJessica Allen Ching, Jonathan Michael Ford, Summer Joy Decker
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Abstract
Aspects of the present invention provide implants for augmentation, stabilization, or defect reconstruction of bone tissue, comprising a scaffold portion structured to provide shape to the implant, the scaffold portion comprising one or more of the following: one or more polylactic acid isomer; one or more polyglycolic acid isomer; and/or allogenic bone material, or similar compound.
Claims41
A bioresorbable implant for augmentation, stabilization, or defect reconstruction of bone tissue, comprising:
- a coextensively bioresorbable scaffold portion structured to provide shape to the implant, the scaffold portion comprising one or more of the following:
- one or more polylactic acid isomer;
- one or more polyglycolic acid isomer;
- and/or
- allogenic bone material;
- the scaffold having a same composition throughout;
- whereby the scaffold portion of the implant is coextensively bioresorbable and in situ promotes its complete resorption and replacement by bone via osteoinduction and/or osteoconduction;
- wherein the implant further comprises one or more bioresorbable screws that secure the implant at an implantation site;
- and
- wherein the implant is configured for application to a bone of the craniofacial skeleton.
A method for augmentation, stabilization, or defect reconstruction of bone tissue, comprising:
- obtaining a bioresorbable implant via 3-D printing, the implant comprising:
- a coextensively bioresorbable scaffold portion structured to provide shape to the implant, the scaffold portion comprising one or more of the following:
- one or more polylactic acid isomer;
- one or more polyglycolic acid isomer;
- and/or
- allogenic bone material;
- the scaffold having a same composition throughout, whereby the scaffold portion is coextensively bioresorbable and in situ promotes its complete resorption and replacement by bone via osteoinduction and/or osteoconduction;
- and
- applying the implant to a site in need of augmentation, stabilization, or defect reconstruction of bone tissue.
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A method for augmentation, stabilization, or defect reconstruction of bone tissue, comprising:
- designing a bioresorbable implant for a customized fit in a subject in which the implant is to be applied;
- obtaining the bioresorbable implant, the bioresorbable implant comprising:
- a coextensively bioresorbable scaffold portion structured to provide shape to the implant, the scaffold portion comprising one or more of the following:
- one or more polylactic acid isomer;
- one or more polyglycolic acid isomer;
- and/or
- allogenic bone material;
- the scaffold having a same composition throughout, whereby the scaffold portion is coextensively bioresorbable and in situ promotes its complete resorption and replacement by bone via osteoinduction and/or osteoconduction;
- and
- applying the implant to a site in the subject in need of augmentation, stabilization, or defect reconstruction of bone tissue.
Dependencies are inferred from the claim text.