System and method of automatic classification of animal behaviors

A system for automatically classifying animal behaviors comprising:

• a vivarium comprising a first set of one or more animals in a plurality of cages;
• wherein a first subset of the first set animals receive by injection a first quantity of cells of the first neoplasm type in a first location in a first organ in each animal in the first subset of animals;
• a set of negative baseline behaviors;
• wherein the set of negative baseline behaviors are behaviors compatible with the first set of animals receiving no injection of cells of the first neoplasm type and no therapeutic treatment;
• a set of positive baseline behaviors, wherein the set of positive baseline behaviors are consistent with unhealthy functioning of the first location of the first organ of the first set of animals;
• at least one sensor proximal to each cage adapted to detect and communicate one or more behaviors of at least some of the first set of animals, the “communicated behaviors”;
• wherein a second subset of the first subset of animals receive a first therapeutic treatment;
• a selected set from the communicated behaviors of the animals in the second subset, the “selected behaviors associated with the first therapeutic treatment,” that are consistent with behaviors in the set of negative baseline behaviors or behaviors consistent with the set of positive baseline behaviors, or both;
• wherein the selected behaviors associated with the first therapeutic treatment are classified responsive to at least both of:
• (a) (the least difference between the quantified, observed behavior of the treated animals and the set of negative baseline behaviors), and (b) (the largest difference between the quantified, observed behavior of the treated animals and the set of positive baseline behaviors).