# US 2016/0354561 A1 · Methods and drug delivery devices using cannabis > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2016/0354561 A1 - Document ID: US20160354561A1 - Status: Published application - Kind: A1 - Application number: 15/118,090 - Filed: 2015-02-11 - Published: 2016-12-08 - Earliest claimed: 2014-02-11 - Assignees: Vapor Cartridge Technology LLC - Inventors: Timothy McCullough - Web page: https://patentgrep.com/patent/US20160354561A1 ## CPC - A61M 11/042: {electrical} - A24C 5/01: Making cigarettes for simulated smoking devices - A24D 1/20: Cigarettes specially adapted for simulated smoking devices - A24F 40/46: Shape or structure of electric heating means - A61K 31/658: {o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol} - A61M 15/0066: {with means for varying the dose size} - A61M 15/06: Inhaling appliances shaped like cigars, cigarettes or pipes - H05B 1/025: {For medical applications} - H05B 3/03: Electrodes - A24F 40/20: Devices using solid inhalable precursors - A24F 40/50: Control or monitoring - A61M 15/002: {with air flow regulating means} - A61M 15/0028: {using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up} - A61M 15/0045: {using multiple prepacked dosages on a same carrier, e.g. blisters} - A61M 15/0086: {Inhalation chambers} - A61M 2207/00: Methods of manufacture, assembly or production - H05B 2203/017: Manufacturing methods or apparatus for heaters - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - A24C: MACHINES FOR MAKING CIGARS OR CIGARETTES - A24D: CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES OF CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES - A24F: SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES (inhaling appliances for medical purposes, shaped like cigars, cigarettes or pipes A61M15/06) - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - H05B: ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL ## Abstract A method of purifying at least one of THC and CBD from a cannabis-containing composition includes heating the cannabis-containing composition to a temperature sufficient to volatilize at least one of THC and CBD into a vapor and condensing the vapor on a substrate. A drug delivery cartridge can include a substrate coated with at least one of THC and CBD and configured to allow for passage of air through the cartridge to volatilize at least one of THC and CBD for inhalation by a user to induce a medicinal or therapeutic effect to the user. A drug delivery system can be used with the drug delivery cartridge and can include a heating element to volatilize at least one of THC and CBD from the coated substrate into a vapor for inhalation. ## Claims ### Claim 1 A drug delivery system comprising: a coated substrate with one or more coating layers, the one or more coating layers including at least one of THC and CBD; and a heating element for heating the coated substrate to a temperature to volatize the at least one of THC and CBD in the one or more coating layers into a vapor inhalable by a user. ### Claim 2 (depends on 1) The drug delivery system of claim 1 wherein the coated substrate is converted into a drug delivery cartridge configured to maximize surface area of the drug delivery cartridge and allow for passage of air through the drug delivery cartridge, in order to volatize at least one of THC and CBD for inhalation by a user when heat is applied to at least one of the drug delivery cartridge or the air passing through the drug delivery cartridge. ### Claim 3 (canceled) ### Claim 4 (depends on 1) The drug delivery system of claim 1, wherein the heating element is contained within a drug delivery device and the drug delivery cartridge is receivable within a receptacle of the drug delivery device to heat the drug delivery cartridge. ### Claim 5 (depends on 4) The drug delivery system of claim 4, wherein the drug delivery device comprises a mister configured to add a mist to the vapor. ### Claim 6 (depends on 5) The drug delivery system of claim 5, wherein the drug delivery device further comprises a misting reservoir hydraulically connected to the mister. ### Claim 7 (depends on 1) The drug delivery system of claim 1, wherein the coated substrate includes first and second electrodes extending laterally on the coated substrate at first and second longitudinal locations, the first and second electrodes each having an electrical resistance sufficient to conduct current laterally along the substrate, the substrate having an electrical resistance high enough to conduct current longitudinally between the first and second electrodes and resistively heat at least a portion of the coated substrate in response to the current conducted therethrough, and the at least one of THC and CBD volatilizes into a gas in response to the resistive heating. ### Claim 8 (depends on 7) The drug delivery system of claim 7, wherein the heating element includes first and second housing electrodes to deliver current between the first and second electrodes on the substrate to resistively heat at least a portion of the coated substrate. ### Claim at position 9 9-18. (canceled) ### Claim 19 A drug delivery product, comprising: a cylindrical structure extending in a longitudinal direction and formed from a substrate of an electrically conductive material, the cylindrical structure comprising: first and second electrodes extending laterally on the substrate at respective first and second longitudinal locations, the first and second electrodes each having an electrical resistance sufficient to conduct current laterally along the substrate; a first substrate portion extending longitudinally between the first and second electrodes, the first substrate portion having an electrical resistance high enough to conduct current longitudinally between the first and second electrodes and resistively heat the first substrate portion in response to the current conducted therethrough; and a first dose of a drug disposed on the first substrate portion and configured to volatilize into a gas in response to the resistive heating of the first substrate portion. ### Claim 20 (depends on 19) The drug delivery product of claim 19, wherein the substrate is rolled to form the cylindrical structure having a spiral cross-section, when viewed from a longitudinal end of the rolled sheet; and further comprising a plurality of electrically insulating spacers positioned to space apart adjacent layers of the substrate. ### Claim 21 (depends on 20) The drug delivery product of claim 20, wherein the first and second electrodes are attached to the substrate prior to rolling the substrate to form the cylindrical structure. ### Claim 22 (depends on 19) The drug delivery product of claim 19, further comprising: a housing configured to receive the cylindrical structure within a cavity in the housing, the cavity sized and shaped to correspond to the cylindrical structure, the housing having first and second housing electrodes around a circumference of the cavity and facing inward toward the cavity, the first and second housing electrodes being positioned longitudinally to respectively contact the first and second electrodes of the cylindrical structure when the cylindrical structure is inserted into the housing, the first and second housing electrodes configured to deliver current between the first and second electrodes of the cylindrical structure. ### Claim 23 (depends on 19) The drug delivery product of claim 19, wherein the cylindrical structure further includes a third electrode extending laterally across the cylindrical structure at a third longitudinal location, so that the second electrode is positioned longitudinally between the first and third electrodes; wherein the third electrode has an electrical resistance small enough to conduct current laterally along the cylindrical structure, wherein the cylindrical structure further includes a second substrate portion extending longitudinally between the second and third electrodes; wherein the second substrate portion has an electrical resistance sufficient to conduct current longitudinally between the second and third electrodes and resistively heat the second substrate portion in response to the current conducted therethrough; and wherein a second dose of the drug is disposed on the second substrate portion and configured to volatilize into a gas in response to the resistive heating of the second substrate portion. ### Claim 24 (depends on 23) The drug delivery product of claim 23, further comprising: a housing configured to receive the cylindrical structure within a cavity in the housing, the cavity sized and shaped to correspond to the cylindrical structure, the housing having first, second, and third housing electrodes around a circumference of the cavity and facing inward toward the cavity, the first, second, and third housing electrodes being positioned longitudinally to respectively contact the first, second, and third electrodes of the cylindrical structure when the cylindrical structure is inserted into the housing, the first and second housing electrodes configured to deliver current between the first and second electrodes of the cylindrical structure, the second and third housing electrodes configured to deliver current between the second and third electrodes of the cylindrical structure. ### Claim 25 (depends on 24) The drug delivery product of claim 24, further comprising: a controller positioned in the housing and configured to deliver current between the first and second housing electrodes to provide the first dose of the drug to a patient, and further configured to deliver current between the second and third housing electrodes to provide the second dose of the drug to the patient. ### Claim 26 (depends on 25) The drug delivery product of claim 25, wherein the controller delivers current between the first and second housing electrodes at a first time to provide the first dose of the drug to a user and delivers current between the second and third housing electrodes at a second time, different from the first time, to provide the second dose of the drug to the user. ### Claim at position 18 27-29. (canceled) ### Claim 30 (depends on 19) The drug delivery product of claim 19, wherein the first and second electrodes are formed integrally with the substrate and are thicker than the first substrate portion. ### Claim 31 (depends on 24) The drug delivery product of claim 24, wherein the housing further comprises a mister configured to add a mist to the volatized first dose of the drug. ### Claim 32 (depends on 31) The drug delivery product of claim 31, wherein the housing further comprises a misting reservoir hydraulically connected to the mister. ### Claim at position 22 33-60. (canceled) ### Claim 61 A method, comprising: forming or providing a sheet of conductive material, the sheet extending in longitudinal and lateral dimensions, the sheet having a plurality of contact portions spaced apart longitudinally and extending laterally across the sheet, the sheet having at least one substrate portion extending longitudinally between a pair of adjacent contact portions, the contact portions having a thickness greater than a thickness of the at least one substrate portion; depositing a drug on the at least one substrate portion, the drug configured to volatilize into a gas in response to resistive heating of the respective substrate portion; and converting the sheet into a cylindrical structure. ### Claim 62 (depends on 61) The method of claim 61, wherein converting the sheet into a cylindrical structure includes rolling the sheet such that the cylindrical structure has a spiral cross-section, when viewed from a longitudinal end of the rolled sheet, and the method further comprising: as the sheet is rolled, placing a plurality of electrically insulating spacers between adjacent layers of the sheet, the spacers being spaced apart to allow a flow of gas therearound. ### Claim 63 (depends on 61) The method of claim 61, wherein converting the sheet into a cylindrical structure includes connecting a first lateral end of the sheet to a second lateral end of the sheet to form the cylindrical structure having a tubular shape, and each of the plurality of contact portions extends around a circumference of the tubular shape. ### Claim 64 (depends on 61) The method of claim 61, wherein the cylindrical structure is configured for use as a drug delivery cartridge. ### Claim 65 (depends on 61) The method of claim 61, wherein the drug includes at least one of THC or CBD.