# US 2016/0354290 A1 · Two-part tooth whitening composition method > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2016/0354290 A1 - Document ID: US20160354290A1 - Status: Published application - Kind: A1 - Application number: 15/243,652 - Filed: 2016-08-22 - Published: 2016-12-08 - Earliest claimed: 2012-03-21 - Assignees: Gosmile, Inc. - Applicants: GoSmile, LLC - Inventors: Jianxun Feng - Web page: https://patentgrep.com/patent/US20160354290A1 ## CPC - A61K 8/22: Peroxides; Oxygen; Ozone - A61K 8/19: containing inorganic ingredients - A61K 8/24: Phosphorous; Compounds thereof - A61K 8/345: {containing more than one hydroxy group} - A61K 8/8164: {Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers, e.g. poly (methyl vinyl ether-co-maleic anhydride)} - A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses - A61K 2800/81: Preparation or application process involves irradiation - A61K 2800/882: Mixing prior to application - A61K 2800/884: Sequential application - A61K 2800/92: Oral administration - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract A method of tooth whitening including the application of a tooth whitening composition to teeth including an aqueous activation part comprising a peroxide activating component, and a peroxide part comprising a peroxide component that does not contain a peroxide stabilizer, wherein the activation part and the peroxide part are each flowable compositions. ## Claims ### Claim 1 A method of whitening at least one tooth, comprising: combining an aqueous activation part comprising (a) a peroxide activating component with (b) a peroxide part comprising a peroxide component to form a tooth whitening composition, and applying the tooth whitening composition to at least one tooth, wherein the peroxide part does not contain a peroxide stabilizer. ### Claim 2 (depends on 1) The method of claim 1, further comprising allowing the tooth whitening composition to remain on the at least one tooth for about 1 minute to about 30 minutes. ### Claim 3 (depends on 1) The method of claim 1, further comprising applying a whitening light to the at least one tooth after applying the tooth whitening composition. ### Claim 4 (depends on 2) The method of claim 2, further comprising applying a whitening light to the at least one tooth after applying the tooth whitening composition. ### Claim 5 (depends on 1) The method of claim 1, further comprising applying a pre-whitening gel prior to applying the tooth whitening composition. ### Claim 6 (depends on 2) The method of claim 2, further comprising applying a pre-whitening gel prior to applying the tooth whitening composition. ### Claim 7 (depends on 3) The method of claim 3, further comprising applying a pre-whitening gel prior to applying the tooth whitening composition. ### Claim 8 (depends on 1) The method of claim 1, wherein the peroxide activating component is selected from the group consisting of sodium tripolyphosphate, tripotassium phosphate, KOH, NaOH, NaHCO3, organic amines, such as triethylamine, salts of boric acid, and combinations thereof. ### Claim 9 (depends on 2) The method of claim 2, wherein the peroxide activating component is selected from the group consisting of sodium tripolyphosphate, tripotassium phosphate, KOH, NaOH, NaHCO3, organic amines, such as triethylamine, salts of boric acid, and combinations thereof. ### Claim 10 (depends on 1) The method of claim 1, wherein the peroxide activating component is present in an amount of about 1 weight percent (wt %) to about 20 wt % based on the total weight of the activation part. ### Claim 11 The method of 1, wherein the activation part further comprises an agent for promoting oral health. ### Claim 12 (depends on 11) The method of claim 11, wherein the agent for promoting oral health is selected from the group consisting of tartar prevention agents, cavity prevention agents, anti-gingivitis agents, and combinations thereof. ### Claim 13 (depends on 1) The method of claim 1, wherein the activation part further comprises a tooth desensitizing agent. ### Claim 14 (depends on 13) The method of claim 13, wherein the tooth desensitizing agent is selected from the group consisting of potassium nitrate, strontium chloride, sodium fluoride, ferric oxalate, and combinations thereof. ### Claim 15 (depends on 1) The method of claim 1, wherein the peroxide component is hydrogen peroxide. ### Claim 16 (depends on 1) The method of claim 1, wherein the peroxide component is present in an amount of about 10 wt % to about 80 wt % based on the total weight of the peroxide part. ### Claim 17 (depends on 1) The method of claim 1, wherein the peroxide part comprises water in an amount of about 1 wt % to about 90 wt % based on the total weight of the peroxide part. ### Claim 18 (depends on 1) The method of claim 1, wherein the pH of the tooth whitening composition after combination of (a) and (b) is about 7 to about 9. ### Claim 19 The method of 1, wherein the viscosity of the tooth whitening composition after combination of (a) and (b) is about 2 cps to about 1000 cps. ### Claim 20 The method of 2, wherein the viscosity of the tooth whitening composition after combination of (a) and (b) is about 2 cps to about 1000 cps.