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US 2016/0312264 A1Published application
Analysis of amino acid copolymer compositions
AssigneeMomenta Pharmaceuticals, Inc.
InventorsXiangping Zhu, Zachary Shriver, Yanjie Jiang, Corinne Bauer, James Eric Anderson, Peter James Ahern
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Abstract
Methods for analyzing, selecting, characterizing or classifying compositions of a co-polymer, e.g., glatiramer acetate are described. The methods entail analysis of pyro-glutamate in the composition, and, in some methods, comparing the amount of pyro-glutamate present in a composition to a reference standard.
Claims1
A method of selecting a batch of a composition comprising an amino acid copolymer, the method comprising:
- providing a batch of a composition comprising an amino acid copolymer;
- measuring the amount of pyro-glutamate (pyro-Glu) in the batch;
- and
- selecting the batch if the amount of pyro-Glu in the batch is within a predetermined range,
- thereby selecting a batch of a composition comprising an amino acid copolymer.
2 more elements
Dependencies are inferred from the claim text.